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Roche and Genentech at

ICML 2025

We will be contributing to topics related to
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12:50 PM
Duration 15mins Room A
Polatuzumab vedotin▼, rituximab, gemcitabine and oxaliplatin (Pola-R-GemOx) for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL): Phase III POLARGO trial
Sancho J-M, Li Z, Vassilakopoulos TP, Viardot A, McMillan A, Dal MS, Pereira J, Kim JS, Qiu L, Batlevi CL, Ibrahim R, Hernandez J, McCall B, Jiang Y, Yan M, Harris W, Musick L, Haioun C, Matasar M
03:30 PM
Duration 10mins Room A
Fixed duration subcutaneous mosunetuzumab▼ in patients with previously untreated high-tumor burden follicular lymphoma: interim results from the Phase II MorningSun study
Budde LE, Burke JM, Sharman JP, Anz B, Zuniga R, Tun AM, Jani P, Biondo JML, Wu M, Mun Y, Chopra VS, Farighi R, Lin T, Villasboas JC, Flinn IW
10:30 AM
Duration 30mins Lugano, Switzerland
Safety and efficacy of mosunetuzumab▼ subcutaneous maintenance following mosunetuzumab▼ plus lenalidomide induction therapy in previously untreated follicular lymphoma
Eyre TA, Cordoba R, Patel K, Serna A, Houot R, Bishton M, Zhang H-L, Zou L, Galvez-Carvajal L, Osborne W, Bachy E, Thieblemont C, Knapp A, Sit J, Chang N, Chen V, Penuel E, Wei MC, Purev E, Morschhauser F
Duration 30mins Lugano, Switzerland
Fixed-duration subcutaneous mosunetuzumab▼ in patients with relapsed/refractory (R/R) follicular lymphoma (FL) with high-risk features: pivotal Phase II study update
Sehn LH, Budde LE, Assouline S, Giri P, Kuruvilla J, Schuster SJ, Yoon S-S, Fay K, Hess G, Dreyling M, Gutierrez NC, Cybulski E, Kwan A, Penuel E, Tracy S, Kuruvilla D, Chen J, Wiebking V, Wei MC, Bartlett NL
Duration 30mins Lugano, Switzerland
Machine learning based unsupervised multimodal analysis identifies patient subsets associated with response to mosunetuzumab ▼ in relapsed/refractory NHL
Hamidi H, Diaz G, Tracy S, Yin S, Wei MC, Penuel E
01:00 PM
Duration 10mins Auditorium
Glofitamab▼ plus R-ICE or as monotherapy in children and adolescents with relapsed/refractory B-cell non-Hodgkin lymphoma: updated analysis from the iMATRIX-GLO study
Minard-Colin V, Vinti L, San Simon AR, Kang HJ, Ducassou S, Gamel K, Wulff J, Chohan S, Hallal M, Negrecea R, Wulff B, Burkhardt B
02:45 PM
Duration 15mins Room A
Fixed-duration outpatient subcutaneous mosunetuzumab▼ + polatuzumab vedotin▼ shows robust efficacy in a Phase II study of relapsed/refractory post-BTKi mantle cell lymphoma
Budde LE, Kamdar M, Assouline S, Ghosh N, Naik S, Nakhoda SK, Chavez J, Ollila TA, Hodson D, Modi D, Bastos-Oreiro M, Ead W, To I, Pham S, Wang J, Wu H, Makadia S, Batlevi CL, Wei MC, Wang ML
03:35 PM
Duration 10mins Polivalente Room
Glofitamab▼+R-CHOP in patients with previously untreated large B-cell lymphoma defined as high risk by circulating tumor DNA (ctDNA) dynamics: primary results
Nijland M, Jardin F, Haioun C, Wrobel T, Joergensen J, Bastos-Oreiro M, Mou E, Lopez JM, Budde LE, Bartlett N, Zaucha J, Garcia-Sancho AM, Ursich E, Kirk S, Jiang Y, Berthier A, Tandon M, Doral M, Falchi L
10:30 AM
Duration 30mins Lugano, Switzerland
Mosunetuzumab▼ demonstrates durable clinical benefit in patients (pts) with complete response (CR) and high-risk relapsed/refractory (R/R) follicular lymphoma (FL)
Cheah CY, Bartlett NL, Matasar M, Schuster SJ, Assouline S, Sehn LH, Kuruvilla J, Giri P, Shadman M, Ku M, Hess G, Gregory GP, Kim WS, Wei MC, Yin S, Sit J, Tracy S, Sabalvaro F, Penuel E, Budde LE
Duration 30mins Lugano, Switzerland
Glofitamab ▼ combined with R-CHOP or Pola-R-CHP in patients with previously untreated diffuse large B-cell lymphoma (DLBCL): final results from the NP40126 study
Topp MS, Tani M, Dickinson M, Ghosh N, Santoro A, Pinto A, Bosch F, Fox CP, Guillermo AL, Gastinne T, Viardot A, Townsend W, Cordoba R, Tilly H, Baumlin P, Berthier A, Kirk S, Wu C, Barrett M, Morschhauser F
Duration 30mins Lugano, Switzerland
Genomic profiling of extranodal (EN) disease in patients (pts) with diffuse large B-cell lymphoma (DLBCL): A combined analysis of POLARIX and GOYA
Lue JK, Morschhauser F, Tilly H, Lenz G, Jardin F, Herrera AF, Sharman JP, Flowers CR, Friedberg JW, Trněný M, Herbaux C, Yan M, Chohan S, Sugidono M, Wang L, Jiang Y, Batlevi CL, Leung W, Harris W, Salles G, Sehn LH
Duration 30mins Lugano, Switzerland
Real-world safety and efficacy of Pola-R-CHP in patients with previously untreated DLBCL: analysis of 500 patients in the POLASTAR study
Nakamura N, Rai S, Sawa H, Miyawaki K, Satake A, Suzuki R, Fujiwara Y, Nagate Y, Ota S, Fujino T, Goto H, Fukuhara N, Sakata-Yanagimoto M, Izutsu K, Nishikori M, Shibayama H, Kumode T, Ennishi D, Shimose T, Inubashiri N, Matsumura I, Akashi K, Kato K
Duration 30mins Lugano, Switzerland
Five-year analysis of an Asia subpopulation with previously untreated DLBCL confirms Pola-R-CHP benefit on outcomes: the POLARIX study
Song Y, Tilly H, Rai S, Zhang H, Jin J, Goto H, Ogawa Y, Shin H-J, Kim WS, Cao J, Eom HS, Yoon DH, Tsai XC-H, Gau J-P, Maruyama D, Zhang L, Song Y, Yang Y, Li W, Huang H, Okumura H, Salles G, Sehn LH, Bu L, Jiang Y, Chohan S, Sugidono M, Batlevi CL, Yan M, Xu C, Huang S, Li W, Zhang Y, Zhu J, Izutsu K
12:30 PM
Duration 15mins Room A
Glofitamab▼ plus gemcitabine and oxaliplatin (Glofit-GemOx) in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL): 2-year follow-up of STARGLO
Abramson JS, Ku M, Hertzberg M, Fox CP, Herbaux C, Huang H-Q, Yoon DH, Kim WS, Zhang H, Abdulhaq H, Townsend W, Mulvihill E, Orellana-Noia V, Ta R, Huang H, Kellemeijn MJ, Belousov A, Bottos A, Lundberg L, Gregory GP
02:30 PM
Duration 15mins Lugano, Switzerland
Mosunetuzumab▼ plus polatuzumab vedotin is superior to R-GemOx in transplant-ineligible patients with R/R LBCL: primary results of the Phase III SUNMO trial
Westin J, Zhang H, Kim W, Fogliatto LM, Maruyama D, Farias DLC, Norasetthada L, Hong H, Ozcan M, Jeon Y-W, Pavlovsky A, Goto H, Olszewski A, Shah N, Hu B, Yin S, Janousek M, Wang J, Batlevi CL, Wei MC, Budde E
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